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1 OMIM reference -
4 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
1 OMIM reference -
1 associated gene
8 signs/symptoms
Squamous cell carcinoma of head and neck
Hereditary cerebral hemorrhage with amyloidosis, Dutch type

ING1 APP
ING3
PTEN
TNFRSF10B


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
ING3
(0.56)
APP



Citations in the biomedical literature:


Squamous cell carcinoma of head and neck
ING1 ING3 PTEN TNFRSF10B
Hereditary cerebral hemorrhage with amyloidosis, Dutch type
APP



Squamous cell carcinoma of head and neck
Hereditary cerebral hemorrhage with amyloidosis, Dutch type

Synonym(s):
- HNSCC
- Head and neck squamous cell carcinoma

Synonym(s):
- HCHWA, Dutch type
- HCHWA-D

Classification (Orphanet):
- Rare oncologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
- Rare systemic or rheumatologic disease

Classification (ICD10):
(no data available)
Classification (ICD10):
(no data available)

Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: adulthood
Average age of death: adult
Type of inheritance: autosomal dominant

External references:
1 OMIM reference -
1 MeSH reference: C535575
External references:
1 OMIM reference -
2 MeSH references: C537944 / D028243

Hereditary cerebral hemorrhage with amyloidosis, Dutch type

Very frequent
- Facial pain / cephalalgia / migraine
- Intracranial / cerebral / meningeal hemorrhage
- Psychic / behavioural troubles
- Psychic / psychomotor regression / dementia / intellectual decline

Frequent
- Intracranial / cerebral calcifications
- Seizures / epilepsy / absences / spasms / status epilepticus
- Transient cerebral ischemia / stroke

Occasional
- Early death / lethality


Squamous cell carcinoma of head and neck

(no data available)